Determination of Metabolic pathways and PPI network of Sarigol in Response to Osmotic stress: An in silico study

Reza Shokri Gharelo


The complexity of plants response to abiotic stress make difficult to manage and target special genes/proteins to be used in improving crop performance. Therefore, understanding and insight into molecular mechanisms recruited by plants under stressful conditions is essence. In this aim, Sarigol, a salt-sensitive cultivar of canola, based on their differentially expressed proteins was studied in silico. The results indicated that the majority of proteins had molecular function of catalytic activity and involvement of these proteins in response to stress underrepresented by Sarigol, whereas proteins involved in cellular and metabolic process were overrepresented. Phylogenetic analysis divided the proteins into 4 groups and protein-protein interaction network prediction illustrated two sets of interacted proteins, while most of proteins did not show any interactions. The results suggested that in the molecular level, Sarigol is unable to respond appropriate actions as are observed in tolerant plants. 


Biological process, Metabolic pathway, Molecular function, PPI network

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